PET/CT and MR Imaging of Central Nervous System Myelomatosis

Abstract

Multiple myeloma essentially targets the axial and appendicular skeleton. From the skull and vertebra, the myelomatous lesions may extend to the brain and spinal canal. Extramedullary central nervous system involvement with leptomeningeal and epidural masses is uncommon and usually demonstrated by MR imaging in symptomatic patients. The authors present a case of clinically unexpected central nervous system myelomatosis initially detected by PET/CT and subsequently confirmed by MR.