Abstract
ABSTRACTObjective: We described pertussis epidemiological trends in Brazil between 2010 and 2015. We also assessed tetanus, diphtheria and acellular pertussis (Tdap) vaccine coverage among pregnant women from 2014, the year of the introduction of Tdap maternal immunization recommendation in Brazil, to 2016.Methods: Epidemiological data for incidence, prevalence, hospitalization, mortality, and maternal vaccination coverage were calculated based on the Brazilian public surveillance databases.Results: The epidemiological data analysis results showed that the pertussis average incidence rate (IR) was 2.19/100,000 inhabitants for all ages, with a peak in 2014 (4.03/100,000 inhabitants) and highest incidence in <1-year-old children (IR = 175.20/100,000). 97.6% of pertussis deaths (405/415) were in <1-year-old children. Maternal immunization coverage was 9.2% in 2014, 40.4% in 2015, and 33.8% in 2016.Conclusions: Pertussis incidence and pertussis-related deaths increased in Brazil from 2010 to 2014 and decreased in 2015. In the two years, 2015 and 2016 that followed the NIP recommendation, Tdap vaccination coverage of pregnant women was low and varying from region to region. More efforts and national plans would help increase awareness and maternal immunization coverage.
Highlights
Pertussis is a highly contagious respiratory disease[1,2] caused by the human-restricted pathogen Bordetella pertussis (B. pertussis).[3]
The present analysis of pertussis surveillance data from the Brazilian Ministry of Health (MoH) showed that from 2010 to 2015, the incidence of pertussis progressively increased in all Brazilian regions
Source data: SI-PNI27 Footnote: acalculated by DATASUS based on their records as follows: number of women vaccinated/number of women in the target population X 100;27 *p < 0.05 (South and North Regions compared to the Southeast, Northeast and Midwest Regions; X2 test); †p < 0.05; ‡p < 0.05
Summary
Pertussis (whooping cough) is a highly contagious respiratory disease[1,2] caused by the human-restricted pathogen Bordetella pertussis (B. pertussis).[3]. The infected person is highly contagious for up to three weeks.[6,7] The disease is transmitted to children
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