Abstract

Background: Reflux occurs in 50% of healthy infants at some point. This is most often a physiological condition and does not require drug treatment. Various studies have shown that the use of drugs affecting gastric acidity (DAGAs) in infants is increasing. This entails disadvantages such as unnecessary exposure of infants to medication and their side effects and a higher cost to society. Objective: To get an image of the current practice in Flanders regarding diagnosis and treatment of gastro-oesophageal reflux disease (GORD) in infants and the associated use of DAGAs. To this end, we determined both parents’ and health care providers’ experiences and perceptions about these treatments. Method: An observational cross-sectional study was conducted in April and May 2019. We developed a questionnaire for parents and three different questionnaires for health care providers (HCPs), including midwives, general practitioners, paediatricians and community pharmacists (CPs). The questionnaire for parents was only available through an online platform. HCPs were questioned face-to-face and through an online platform. Results: This study made clear that the counselling of children with GORD is multidisciplinary as the median number of counselling HCPs is 3 (interquartile range (IQR) = 2–4). 63% of the included 251 parents also seek support through online forums and groups. 60% of parents report that no physical tests were performed before DAGAs were prescribed and 39% of parents additionally state they perceived no effect of the prescribed DAGAs. Although parents reported to understand HCPs well (average score 7.4/10), satisfaction with care and information provision was scored lower (between 4.8 and 6.1/10). On the other hand, 234 HCPs answered the questionnaire, of which 89 midwives, 78 community pharmacists and 67 physicians. Only 45 HCPs indicate that guidelines to diagnose or treat GORD are clear. Physicians confirm they perform very little physical testing before starting DAGAs. Provided nonmedical measures to patients are largely in line with the European guidelines, however perceived effectiveness is moderate. Conclusion: Parents are in need for more information about tests, nutrition and (non)medical measures. HCPs on the other hand are in need for clear guidelines on diagnosing and treating GORD.

Highlights

  • Gastro-oesophageal reflux (GOR) is defined as the retrograde flow of gastric content into the oesophagus and is very common in the first year of life [1,2]

  • General practitioners, paediatricians, community pharmacists and midwives were questioned about gastro-oesophageal reflux disease (GORD) in infants and the associated use of drugs affecting gastric acidity (DAGAs)

  • This study made clear that the counselling of children with GORD is multidisciplinary

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Summary

Introduction

Gastro-oesophageal reflux (GOR) is defined as the retrograde flow of gastric content into the oesophagus and is very common in the first year of life [1,2]. A recent systematic review reported a pooled prevalence of GORD symptoms in infants of 26.9% (95% confidence interval [CI] 20.1–33.7) ranging from 23.1% to 40.0%. Studies reporting prevalence at different time points up to the age of 13 months, showed a significant declining with increasing age [1]. Reflux occurs in 50% of healthy infants at some point. This is most often a physiological condition and does not require drug treatment. Various studies have shown that the use of drugs affecting gastric acidity (DAGAs) in infants is increasing. This entails disadvantages such as unnecessary exposure of infants to medication and their side effects and a higher cost to society. Method: An observational cross-sectional study was conducted in April and

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