Abstract

Regarding the diet treatment of diabetic nephropathy, protein restriction has been recommended. American Diabetes Association (ADA) proposed protein restriction guidelines in the 2008 edition. However, this comment was deleted in the 2013/2019 edition, because of insufficient evidence. A recent report showed that the intake of plant protein has a protective effect on the decrease of estimated glomerular filtration rate (eGFR), and the intake of animal protein has neither protection nor deterioration. There are controversies about the relationship between protein intake and the reduction of renal function. Further research will be expected for diabetic nephropathy, diabetic kidney disease (DKD), and chronic kidney disease (CKD).

Highlights

  • Diabetes Association (ADA) proposed protein restriction guidelines in the 2008 edition

  • The description of protein restriction for patients with kidney disease began in the 1987 edition [7]

  • The Japan Diabetes Association (JDA) showed the comment that protein restriction may be effective in suppressing the progression of diabetic nephropathy after the overt nephropathy stage, but clinical evidence is insufficient

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Summary

Introduction

Diabetes Association (ADA) proposed protein restriction guidelines in the 2008 edition. Keywords Diabetic Nephropathy, American Diabetes Association (ADA), Estimated Glomerular Filtration Rate (eGFR), Diabetic Kidney Disease (DKD), Chronic Kidney Disease (CKD) Abbreviations American Diabetes Association (ADA); Estimated Glomerular Filtration Rate (eGFR); Diabetic Kidney Disease (DKD); Chronic Kidney Disease (CKD) A protein-restricted diet has been often used for patients with impaired renal function.

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