Abstract
The distribution of the electric field in the brain during tDCS is one of the main factors that determine the outcome of stimulation. Currently, knowledge of the field within the brain comes mainly from computational models. A review of modelling studies reveals a large inter-individual variability of the electric field produced in the stimulation target due to variations in: cortical anatomy; scalp, skull and CSF thickness; head size; age; etc. Some studies specifically predict that the electric field in pediatric heads is higher than in adult heads. In addition computational models can also be used to determine optimal electrode positions and currents to achieve the desired field strength in the cortical target. This suggests that personalized optimization of stimulation parameters based on individual head models may be an effective approach to increase efficacy and ensure safety of tDCS in pediatric subjects.
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