PERSONALIZED FLOW DIVISION METHOD BASED ON THE LEFT-RIGHT CORONARY CROSS-SECTIONAL AREA

Abstract

This paper proposes a personalized method to estimate blood flow distribution based on the cross-sectional area of the left-right coronary artery openings. According to the cross-sectional area of the left-right coronary artery in 30 cases, a personalized flow distribution model was derived. A 0D/3D geometric multiscale model was used for the numerical simulation of FFR. To evaluate the accuracy of the cross-sectional area method, invasive FFR was used as the standard. The diagnostic efficiency of the proposed method was verified through the simulation results of the volume and the fixed ratio methods. The flow of the left-right coronary artery was proportional to the 3/4 power of the cross-sectional area. The 95% LOA between the cross-sectional area method, volume method, fixed ratio method and FFR were [Formula: see text]0.06 ([[Formula: see text]0.22, 0.10]), [Formula: see text]0.03 ([[Formula: see text]0.35, 0.28]), and [Formula: see text]0.05 ([[Formula: see text]0.30, 0.20]), the accuracy values were 94.44%, 77.78%, and 77.78%, respectively. Flow distribution based on the cross-sectional area represents the supply and demand relationship of the myocardium. The flow of the left-right coronary arteries is proportional to the 3/4 exponent of the cross-sectional area, which affects the accuracy of FFRCT by affecting the exit boundary conditions of the 0D/3D model.