Personalized diagnostics and treatment of breast cancer

Abstract

Breast cancer can exist for long periods as non-invasive or invasive but non-metastatic disease. Early detection of breast cancer, for example by mammography screening, significantly improves a woman ’ s chances of survival. If breast cancer is diagnosed and treated while it is confined to the breast, the cure rate can approach 100%. However, mammography screening is far from perfect in terms of sensitivity and specificity of cancer detection. There is a significant clinical need for accurate and highly sensitive tests for early detection of breast cancer. Target applications are screening of high-risk groups, particularly younger women (under the age of 50) from high-incidence families, and breast cancer patients to detect the primary metastasis and migratory route, to direct treatment and the early detection of recurrence when screening breast cancer patients.