PERSISTENT SOLITARY FIBROUS TUMOR APPEARING AS AN AGGRESSIVE MANDIBULAR RADIOLUCENCY

Abstract

We report an unusual case of solitary fibrous tumor (SFT) with persistent behavior. A 41-year-old female was referred for evaluation due to tender swelling on the right chin of unknown duration. Intraoral examination revealed a firm well-circumscribed mass in the right lower buccal vestibule and imaging exams showed slight buccal cortical resorption. An incisional biopsy was performed, and microscopic analysis revealed cellular proliferation of bland spindle cells, admixed with dense collagen, prominent staghorn blood vessels, and positivity for CD34, CD99, Bcl-2, and positive nuclear staining for STAT6, rendering a diagnosis of SFT. Five years after complete surgical excision of the tumor, the patient presented a 3 cm, ill-defined expansive radiolucency in the right mandibular body, which was microscopically diagnosed as persistent SFT. No signs of malignancy were observed. SFT closely related to the mandible may persist after long-term follow-up, appearing as aggressive and extensive radiolucency. We report an unusual case of solitary fibrous tumor (SFT) with persistent behavior. A 41-year-old female was referred for evaluation due to tender swelling on the right chin of unknown duration. Intraoral examination revealed a firm well-circumscribed mass in the right lower buccal vestibule and imaging exams showed slight buccal cortical resorption. An incisional biopsy was performed, and microscopic analysis revealed cellular proliferation of bland spindle cells, admixed with dense collagen, prominent staghorn blood vessels, and positivity for CD34, CD99, Bcl-2, and positive nuclear staining for STAT6, rendering a diagnosis of SFT. Five years after complete surgical excision of the tumor, the patient presented a 3 cm, ill-defined expansive radiolucency in the right mandibular body, which was microscopically diagnosed as persistent SFT. No signs of malignancy were observed. SFT closely related to the mandible may persist after long-term follow-up, appearing as aggressive and extensive radiolucency.