Abstract
SLE patients are at risk of tuberculosis (TB) infection due to both secondary immunosuppression and intrinsic defects in innate immunity. On the other hand infection can also perpetuate the development of an autoimmunity [1,2].
Highlights
SLE patients are at risk of tuberculosis (TB) infection due to both secondary immunosuppression and intrinsic defects in innate immunity
Here we report a case of pulmonary tuberculosis reactivation in a SLE patient
After commencing anti TB treatment, her SLE activity remitted with resolution of proteinuria and cytopenia, allowing steroid tapering
Summary
Introduction SLE patients are at risk of tuberculosis (TB) infection due to both secondary immunosuppression and intrinsic defects in innate immunity. On the other hand infection can perpetuate the development of an autoimmunity [1,2]. Objectives Here we report a case of pulmonary tuberculosis reactivation in a SLE patient. The lupus activity was not responsive to heavy immunosuppressants. It was only controlled after commencement of anti TB treatment.
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