Abstract

Background and aims: Merkel cell carcinoma (MCC) is a rare skin cancer with a high rate of recurrence. Serum antibodies to Merkel cell polyomavirus oncoprotein (AMERK) are present in 50% of patients and can be used to monitor for recurrence after achieving remission. It is expected that 90% 0f AMERK titers will normalized by one year after successful treatment and continue to fall subsequently. Our aim is to describe the longitudinal clinical course in patients with MCC and elevated AMERK levels despite having no evidence of disease.

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