Abstract
to verify persistence of metabolic syndrome (MetS) and components in overweight children and adolescents, as well as its relation to socioeconomic and demographic characteristics and to the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) score. a two-point longitudinal study: at enrollment and after a 24-month interval, with 133 individuals ages from two to 18 years. The demographic anthropomorphic and blood variables were evaluated. Analysis was carried out by simple and paired association tests, as well as multiple logistic regression. persistent MetS was observed in 38.3% of the sample, associated cardiovascular risk (ACR) in 79.7%, reduction in arterial pressure and do HDL-c. After adjusting for age and sex, excess weight (ExpB: 0.182; CI: 0.059-0.561), low HDL-c (ExpB: 9.247; CI: 1.157-73.930) and high LDL-c (ExpB:1.915; CI: 0.921-3.979) were associated with persistent MetS. persistent MetS was associated with obesity, HDL-c and LDL-c, but not with the PDAY score.
Highlights
Brazil is currently undergoing economic, social and demographic changes, with repercussions on living, health and working conditions, including the diet of the population
There is no consensus for the diagnosis of metabolic syndrome (MetS) in children and adolescents, it is accepted that the coexistence of three or more cardiometabolic risk factors, such as arterial hypertension, abdominal adiposity, hypertriglyceridemia, reduction of HDL-cholesterol and glucose intolerance or type 2 diabetes mellitus (DM2), characterizes its presence[5,6], it may or may not be associated with inadequate lifestyle, socioeconomic condition, sedentarism, physical inactivity and smoking[7]
Brazil has been presenting an increase in MetS among the young and especially in the obese, with a consequent increase in cardiovascular diseases (CVD)[11] The PDAY cardiovascular risk score (Pathobiological Determinants of Atherosclerosis in Youth)(12) is a global risk algorithm including multiple risk factors, such as sex, age, serum lipoprotein concentrations, smoking, hypertension, obesity, and hyperglycemia
Summary
Brazil is currently undergoing economic, social and demographic changes, with repercussions on living, health and working conditions, including the diet of the population. Brazil has been presenting an increase in MetS among the young and especially in the obese (the prevalence in the interior of the Northeast is 21.3% and 36.2% in João Pessoa, capital of Paraíba), with a consequent increase in CVD[11] The PDAY cardiovascular risk score (Pathobiological Determinants of Atherosclerosis in Youth)(12) is a global risk algorithm including multiple risk factors, such as sex, age, serum lipoprotein concentrations, smoking, hypertension, obesity, and hyperglycemia It was developed with the purpose of estimating the probability of atherosclerotic lesions in adolescents and young adults[13]; with physical inactivity and sedentarism as aggravating risk factors[14,15,16]
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