Abstract
Persistent immune-tolerance to non-inherited maternal antigen (NIMA) allows successful kidney transplantation in regraft patient: Case report
Highlights
Kidney transplantation is the therapy of choice for patients with end stage renal disease
Al Attas RA (2017) Persistent immune-tolerance to non-inherited maternal antigen (NIMA) allows successful kidney transplantation in regraft patient: Case report transplantation antigen presenting cells (APC) from the graft will recognize inherited paternal antigens (IPA) of the recipient when the mother is the donor, when the sibling is the donor the graft derived –cells will only recognize inherits the maternal HLA-antigen (IMA) that they encountered during fetal life, so possibly that the anti -IPA maternal response is responsible for undermining tolerance to NIMA
We describe here a case of successful second transplant due to persistence immune tolerance to NIMA despite repeated exposure to maternal antigens
Summary
Persistent immune-tolerance to non-inherited maternal antigen (NIMA) allows successful kidney transplantation in regraft patient: Case report.
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