Abstract
One of the complications of neurotrophic keratopathy is the breakdown of the corneal epithelium. This can progress to non‐healing persistent epithelial defects (PED) which are challenging to manage and can lead to corneal ulceration, scarring and perforation.The causes of epithelial breakdown, prevention and contemporary medical and surgical management will be discussed during this talk. The use of conservative methods available to all clinical settings all they way to more sophisticated surgical methods available in tertiary referral centres, will be presented and discussed.
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