Abstract
To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients. MVDs performed in Nanjing Drum Tower Hospital in 2017 were retrospectively studied, and 326 patients with HFS were classified into two groups based on whether AMR disappeared or persisted following MVD. The clinical features, treatment efficacy and postoperative complications were compared between the two groups. 305 patients with disappeared AMR after decompression were classified as Group A. In Group B, the 21 patients exhibited persistent AMR after successful MVD. The preoperative duration of symptoms in Group B was significantly longer than that in Group A (P < 0.001), and no significant difference was identified between the two groups in terms of gender, side, age and offending vessels (P > 0.05). The immediate postoperative cure rate of Group A (88.9%)was significantly higher than that in Group B (28.6%, P < 0.001), furthermore, the two groups were not different in the long-term outcome and the incidence of surgical complications (P > 0.05). The long preoperative duration of HFS patients may account for persistent AMR after successful decompression, and it is more likely for these patients to get delayed cured, the long-term outcomes showed no difference compared to those in patients with disappeared AMR after MVD.
Highlights
To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients
After Analyzing the data with SPSS Statistics version 22.0, we found that the preoperative duration of symptoms in Group B was significantly longer than that in Group A (P < 0.001), and no significant difference was identified in terms of age, gender, affected side and offending vessels (P > 0.05) between the two groups (Table 1)
By comparing the clinical features of the two groups, this study reported that the preoperative duration of the patients exhibiting persistent AMR was significantly longer that of AMR-disappear patients
Summary
To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients. In Group B, the 21 patients exhibited persistent AMR after successful MVD. The long preoperative duration of HFS patients may account for persistent AMR after successful decompression, and it is more likely for these patients to get delayed cured, the long-term outcomes showed no difference compared to those in patients with disappeared AMR after MVD. Existing s tudies[6,7,8] verified that abnormal muscle response (AMR) can help surgeons to identify the offending vessels, and its disappearance commonly indicates spasm free after decompression. The major aim was to delve into the cause of persistent AMR after MVD and the clinical outcomes of these patients
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