Abstract

The duration of the humoral immune response in children infected with severe acute respiratory syndrome coronavirus 2 is unknown. We detected specific IgG 6 months after infection in children who were asymptomatic or had mild symptoms of coronavirus disease. These findings will inform vaccination strategies and other prevention measures.

Highlights

  • The duration of the humoral immune response in children infected with severe acute respiratory syndrome coronavirus 2 is unknown

  • The nature and persistence of the immune response generated by children after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is unknown

  • We investigated the humoral immune response to SARS-CoV-2 in children and adults as part of a longitudinal cohort study in Melbourne, Victoria, Australia

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Summary

Introduction

The duration of the humoral immune response in children infected with severe acute respiratory syndrome coronavirus 2 is unknown. The nature and persistence of the immune response generated by children after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is unknown. We investigated the humoral immune response to SARS-CoV-2 in children and adults as part of a longitudinal cohort study in Melbourne, Victoria, Australia.

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