Abstract
The importance of peroxisomes in central nervous system (CNS) comes from the observation that in several peroxisomal disorders, such as Zellweger syndrome, Adrenoleukodystrophy, Rhizomelyc chondrodysplasia punctata etc, severe neurological impairments were observed. They have been involved in several physiological processes in brain, such as protection against reactive oxygen species (ROS), myelinogenesis and very long chain fatty acid metabolism.KeywordsRetinoic Acid ReceptorZellweger SyndromePeroxisomal EnzymePeroxisomal DisorderSevere Neurological ImpairmentThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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