Abstract

The complexity of the biological sample to be tested requires the sensor to have a wide monitoring range, accurate selectivity, and excellent environmental tolerance. Here, we report a new strategy of in situ transformation of perovskite to form a heterojunction and combined with bioactive enzyme protective substances, thereby achieving a collection of multiple sensing properties. Through in situ conversion of TiO2 to SrTiO3 to form a heterojunction to provide high oxidation activity and protection for GOx through PDA, the TiO2/SrTiO3/PDA/GOx biosensor achieves an ultra-wide linear detection range of 0–32 mM. Such a range can effectively monitor the physical condition of people with high blood sugar levels (above 20 mM). Good stability, anti-interference, environmental tolerance, and accurate human blood detection all prove the excellent sensing performance and practical application potential of the TiO2/SrTiO3/PDA/GOx biosensor.

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