Abstract

Recently, Read, Douglas and Simmons (1959) reported certain effects of urea on some cestodes of the order TETRAPHYLLIDEA. They found that when removed directly from the hosts, Callibothrium verticillatum and Phyllobothrium foliatum contain high concentrations of urea, averaging 3.7 percent of the dry weight in the case of Calliobothrium. They presented evidence that urea is an osmotically active component of the tissues of these worms. In salt solutions not containing urea, the worms undergo an initial hydration of large magnitude, subsequent volume regulation being accompanied by a loss of urea from the tissues. Addition of 200 mM of urea per liter of salt solution resulted in a great, though not total, diminution of the initial hydration, and the return of the worms to the approximate original weight was more rapid. The present studies are an examination of the kinetic aspects of urea permeation and exchange in some TETRAPHYLLIDEA.

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