Permanent exocrine and endocrine pancreatic deficiency following hemolytic uremic syndrome

Abstract

A 2-year-old previously healthy boy had development of hemolytic anemia and acute kidney failure caused by hemolytic uremic syndrome (HUS), secondary to Escherichia coli 122787diarrhea. The patient was treated with hemodialysis and never received steroids. He had a stormy course complicated by shock. During the illness, he had development of pancreatitis with markedly elevated amylase and lipase followed by persistent hyperglycemia without evidence of ketosis. The hyperglycemia required continuous intravenous insulin infusion and was associated with exocrine pancreatic deficiency.