Abstract

Investigators from Okazaki City Hospital, and other centers in Japan retrospectively evaluated the clinical features, ultrasonography, and EEG findings in 22 preterm infants with PVHI and 49 with PVL.

Highlights

  • Investigators from Okazaki City Hospital, and other centers in Japan retrospectively evaluated the clinical features, ultrasonography, and EEG findings in 22 preterm infants with PVHI and 49 with PVL

  • Cranial ultrasonography (US) in infants with PVHI shows periventricular intraparenchymal echodensity (IPE) at 1-3 days after birth, whereas cystic changes in deep white matter are seen in infants with cystic PVL at 1-3 weeks

  • US had high sensitivity (100%) and specificity (93%) in detecting grade III germinal matrix hemorrhage (GMH) but poor sensitivity (0%) in detection of intraventricular hemorrhage

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Summary

HEADACHE AND SLEEP DISORDERS

Investigators from Sapienza University, Italy, studied the prevalence and treatment of sleep disorders in children with migraine. Sleep apnea, sleep bruxism and restless legs syndrome often leads to improvement of migraine. Prodromal symptoms of migraine (yawning, drowsiness, irritability, mood changes, hyperactivity) support a direct role for the dopaminergic system that is involved in sleep-related movement disorders. Child education and lifestyle modification including sleep hygiene have a significant role in the management of migraine. Comorbid sleep disorders should be screened in children with migraine. Sleep and headache in children: specific pattern in migraine, implication for the treatment. The association of migraine and sleep disorders, especially restless legs syndrome, is discussed by another Italian group of investigators [1]

VASCULAR DISORDERS
Findings
RITUXIMAB IN AUTOIMMUNE CNS DISEASE
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