Peritumoral Edema and Regional Cerebral Blood Flow in Brain Tumors

Abstract

Brain tumor is often associated with peritumoral edema and the extent of the edema has been reported to be related to many factors especially meningiomas. The possible mechanisms for the production of severe edema surrounding meningioma include clinical evolution, tumor size, location, histological subtype, cellularity, vascularity, secretory-excretory activity, mechanical compression of a draining vein and disruption of the cortical layer between the tumor and the underlying white matter [1–5]. However, any of these factors are not sufficient to explain the production of peritumoral edema in brain tumors. In this study, peritumoral edema was analysed with special attention to the regional cerebral blood flow (rCBF).