Abstract
To evaluate if latex coated polypropylene mesh leads to less adhesions formation. 90 rats were distributed in three groups. Group I (control) was submitted to median laparotomy and posterior synthesis; Group II (polypropylene) was submitted to a segment resection of the abdominal wall, and the defect was corrected with a polypropylene mesh; Group III using the new material (latex coated polypropylene). After 45 days the euthanasia procedure was done and the adhesions were evaluated in 2 ways: 1) classification in a grading system; 2) evaluation of the adhesion area, which was calculated by resection of the adhesions after dying with Indian blue ink. The classification in a grading system showed that Group III animals had less adhesions formation (P<0.05), but the evaluation of the adhesion area did not show any difference (P>0.05). The severe complications (fistula, evisceration and obstruction), which were lethal, were not reduced by the latex coated material. Latex coated polypropylene causes fewer adhesion formations than polypropylene alone, although it does not diminish the severe early complications.
Highlights
The major defects in the abdominal wall sometimes are difficult to repair and basically depend on three aspects, according to Rahal1: 1) circumstances that impair cicatrisation, such as obesity, chronic pneumopathies, cirrhosis, malnutrition, prostatic obstruction, and others; 2) circumstances that hamper abdominal wall synthesis, due to abdominal hypertension, such as critical abdominal traumas and serious infections; 3) circumstances that facilitate dehiscence and evisceration, such as lack of strictness with asepsis and anti-sepsis, inappropriate incisions, inadequate hemostasis and under tension suture
Group I was submitted to median laparotomy and posterior synthesis; Group II was submitted to a segment resection of the abdominal wall, and the defect was corrected with a polypropylene mesh; Group III using the new material
After 45 days the euthanasia procedure was done and the adhesions were evaluated in 2 ways: 1) classification in a grading system; 2) evaluation of the adhesion area, which was calculated by resection of the adhesions after dying with Indian blue ink
Summary
The major defects in the abdominal wall sometimes are difficult to repair and basically depend on three aspects, according to Rahal1: 1) circumstances that impair cicatrisation, such as obesity, chronic pneumopathies, cirrhosis, malnutrition, prostatic obstruction, and others; 2) circumstances that hamper abdominal wall synthesis, due to abdominal hypertension, such as critical abdominal traumas and serious infections; 3) circumstances that facilitate dehiscence and evisceration, such as lack of strictness with asepsis and anti-sepsis, inappropriate incisions, inadequate hemostasis and under tension suture. The most used prosthesis in our region is the polypropylene one, introduced by Usher[4,5] in 1959, a high-density polyethylene derived from ethylene gas It differs from the conventional polyethylene in various aspects: a) a crystallized molecular structure which confers more resistance; b) it can be produced in a monofilament way; c) it has more chemical resistance and d) it tolerates high temperatures, what allows autoclave sterilization. In his preliminary study, Usher promptly demonstrated that
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
