Abstract
Due to the increasing number of patients with diabetes and the aging of society, the number of patients with diabetes and peripheral arterial occlusive disease (PAOD) is constantly increasing. Diabetes is a major risk factor for the development and progression of PAOD and the combination of both diseases worsens the prognosis. Timely diagnosis and therapy appropriate to the clinical stage are important. Comparable to other atheromatous vascular diseases, treatment of vascular risk factors is essential. The cornerstones of treatment are structured exercise training, antiplatelet drugs, and statins. The combination of acetylsalicylic acid (aspirin) and rivaroxaban is a further option for vascular patients at high risk for ischemia. In patients with diabetes, the long-term results of revascularization are often unsatisfactory. Therefore, the indication for either endovascular therapy or open surgery must be narrowly defined in the stage of claudication. In the case of critical limb-threatening ischemia revascularization must be immediately done.
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