Abstract
Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total of 239 patients were randomly assigned to either one application of SH alone or one application of SH preceded by one application of 70% ethanol (ET-SH). Catheter colonization, defined as a catheter tip culture growing >1000cfu of a micro-organism per millilitre, occurred in 29 patients (33% of 89 colonizations per 1000 catheter-days) in the SH group and in 31 patients (33% of 126 colonizations per 1000 catheter-days) in the ET-SH group.
Highlights
Peripheral venous catheter (PVC) is the medical device most commonly used in hospitals
Four patients in the sodium hypochlorite (SH) group and three in the ET-SH group did not benefit from the study antiseptics and were secondarily excluded
Sixty (33%) colonized catheters were identified among the catheters cultured: 29 (33% of 89 colonizations per 1000 catheter-days) in the SH group and 31 (33% of 126 colonizations per 1000 catheter-days) in the ET-SH group (Supplementary Table S3, Figure 1)
Summary
Peripheral venous catheter (PVC) is the medical device most commonly used in hospitals. B. Drugeon et al / Journal of Hospital Infection 120 (2022) 123e126 patients on average, requiring premature catheter removal before end of treatment. Treatment interruption may be detrimental to patients [1,2]. Catheter replacement results in patient discomfort and additional costs due to the use of new medical devices and paramedical resources. Though rare, infectious complications are associated with prolonged hospitalization, increased treatment costs, and mortality
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