Abstract
BackgroundT-cell lymphomas involve the testis infrequently, which deserve special attention because of the poor prognosis and the need to make an appropriate diagnosis, which could lead to a better therapeutic strategy.Case presentationA 40-year-old man presented with right testicular swelling for past three months. The swelling was painless, hard and rubbery. Testicular ultrasound showed diffuse increase in size of the testicle, with alteration in its echogenicity. The patient underwent orchidectomy, and based on histopathological and immunohistochemical tests, a peripheral T-cell lymphoma, not otherwise specified was diagnosed.ConclusionTesticular peripheral T-cell lymphomas are rare and aggressive cancers, with clinical differentials of seminoma and non-neoplastic conditions.
Highlights
T-cell lymphomas involve the testis infrequently, which deserve special attention because of the poor prognosis and the need to make an appropriate diagnosis, which could lead to a better therapeutic strategy
In primary T-cell lymphomas, most case reports are of T-cell/Natural Killer (NK) cell lymphoma with very few cases of peripheral T-cell lymphoma (NOS)
Even for patients with stage I disease and good-risk International prognostic index (IPI), the outcome seems worse than that reported for diffuse large cell lymphoma (DLCL) at other sites [7,8,9]
Summary
Testicular lymphomas comprise 5% of testicular malignancies and these account for about 1% of all lymphomas. A non-tender lump measuring 4.0 × 3.5 cm, firm-to-hard in consistency, was present as a right testicular swelling. It was associated with slight skin puckering. For this sonographic appearance was seminoma and orchitis His erythrocyte sedimentation rate (ESR) was within normal range and the Montoux test for Mycobacterium tuberculosis was negative. His complete blood counts at the time of presentation were within normal limits. Histologic examination of the specimens revealed a diffuse proliferation of malignant round cells within the interstitium of the testicular parenchyma. The study was not experimental and no identifiable material was used in the manuscript, so this study did not require ethical approval
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