Abstract
Peripheral odontogenic myxoma (POM) is a rare and extra-osseous variant of odontogenic myxoma (OM), classified as a relatively rare benign odontogenic tumor, yet presenting locally aggressive behavior. The objective this manuscript is to report a case of POM in a 75-year-old patient, located in the right maxilla, and in addition, to perform a literature review of the data in relation to clinical, radiographic aspects, hypothesis of diagnosis, and treatment. A male patient, 75 years old, clinical examination constact the presence of a nodule, with a smooth surface, on the right upper alveolar ridge, measuring 20 x 25 mm, with a color similar to the mucosa, a softened consistency, involving teeth 14 and 15, and with an undetermined time of evolution was observed. The diagnostic hypothesis was a peripheral ossifying fibroma and differential diagnosis of peripheral giant cell lesion. An excisional biopsy was performed together with extraction of the involved teeth. Histopathological examination and histochemical reaction was confirm the histopathological diagnosis of POM. The reported case is extremely rare due to the clinical presentation of the lesion, causing bone resorption with tooth mobility. In addition, the age range of involvement is very different from that presented in the literature, between the second and fourth decade of life. The final diagnosis was very important, as it is a lesion with a great potential for recurrence, long-term follow-up should be more careful, and in case of recurrence, a new intervention must be performed.
Highlights
Odontogenic myxoma (OM) is an unusual, slow growth, benign mesenchymal tumor, locally invasive, and classified as an odontogenic tumor due to the great histological similarity that it presents with the odontogenic ectomesenchyme (Dotta et al, 2020; Francisco et al, 2016; Kawase-Koga et al, 2014; Leiser et al, 2009)
OMs are classified into two variants: central odontogenic myxoma, and peripheral odontogenic myxoma (POM) (Aytac-Yazicioglu et al, 2008; Tasnime et al, 2016; Singh et al, 2013)
POM articles with a different focus than the one mentioned in the inclusion criteria; 3. hybrid tumors partially composed of a POM,; and 4. any language other than English
Summary
Odontogenic myxoma (OM) is an unusual, slow growth, benign mesenchymal tumor, locally invasive, and classified as an odontogenic tumor due to the great histological similarity that it presents with the odontogenic ectomesenchyme (Dotta et al, 2020; Francisco et al, 2016; Kawase-Koga et al, 2014; Leiser et al, 2009) This is in addition to its location in areas of tooth support in the maxillary bones, and its occasional association with missing or unbroken teeth (Oliveira et al, 2018; Raubenheimer et al, 2012; Aytac-Yazicioglu et al, 2008; Kapoor et al, 2015). There is no consensus in the literature as to the formation of this OM subtype (Aytac-Yazicioglu et al, 2008; Perrotti et al, 2006; Chrcanovic & Gomez, 2019)
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