Abstract
Peripheral blood T-cell subpopulations were evaluated in 32 patients affected by viral warts and in 32 unaffected individuals belonging to a control group. A significant decrease was found in total lymphocytes as well as OKT3 and OKT4 subsets among affected patients. A significant negative correlation was also found between OKT3 and OKT4 numbers as well as OKT4/OKT8 ratio and duration and extent of lesions. A significant positive correlation was found between the duration and the extent of lesions and the percentage of OKT8 subsets, but not the total number of OKT8. These data confirm that a cell-mediated immune deficiency is present in patients with viral warts. We then discuss whether the decrease of cellular immunity in these patients is a primary event or, rather, the result of persistent verrucosis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
