Abstract
In the first study, injection of NPY into the hypothalamic paraventricular nucleus (PVN) caused a robust feeding effect that was attenuated by intravenous infusions of glucose, but not fructose. It is suggested that increased blood glucose has a direct central effect on NPY feeding mechanisms. In a second study, and contrary to a previous report, peripheral administration of CCK-8 had a marked satiety effect in NPY-treated rats. Thus, NPY-induced feeding is, at least for a short time, possibly subject to the satiating action of prandially-released CCK. In a final study, NPY was shown to be without effect on gastric emptying of a solid test meal.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
