Perioperative risk factors for cone reconstruction of Ebstein' s anomaly

Abstract

Objective The study was designed to analyze the risk factors for perioperative adverse events in Ebstein's anomaly(EA) after cone construction. Methods A retrospective analysis was performed on EA cases undergoing cone construction in pediatric heart center of Beijing Anzhen Hospita from January 2010 to January 2017. Patients were divided into group A(no adverse events occurred) and group B(adverse events occurred) according to the presence or not of perioperative adverse events. Univariate and multivariate logistic regression analysis was performed with 9 preoperative and intraoperative variables as the predicted risk factors. Results The incidence of adverse events was 13.1%. Univariate logistic regression analysis showed that preoperative percutaneous oxygen saturation(SpO2)≤ 0.90(P=0.001, OR=10.578) and extracorporeal circulation time(P=0.034, OR=1.021) were risk factors for perioperative adverse events. Results of multivariate logistic regression analysis: preoperative SpO2≤ 0.90 was an independent risk factor for perioperative adverse events(P=0.002, OR=9.108). In 64 cases(64.6%) with atrial septum defect, there was no significant correlation between preoperative SpO2 and preoperative tricuspid regurgitation(P=0.838, r=0.026). Conclusion Preoperative SpO2≤0.90 is an independent risk factor for adverse events in the perioperative period of cone reconstruction. It is a simple and efficient method to evaluate the operation difficulty and determine the prognosis by SpO2. Key words: Cone reconstruction; Preoperative; Percutaneous oxygen saturation