Abstract
BackgroundHead and neck cancers are aggressive cancers, most clinical studies focused on the prognosis of patients with head and neck cancer. However, perioperative mortality was rarely mentioned.MethodsA retrospective analysis was performed using all head and neck cancer patients admitting in the Department of Oral and Maxillofacial Surgery of the Second Xiangya Hospital, Central South University from January 2010 to December 2019. The analysis of overall survival and progression-free survival were performed using the Kaplan–Meier method, and cross tabulation with chi-squared testing was applied to analyze the difference in parameters between groups.ResultsFrom January 2010 to December 2019, a total of 6576 patients with head and neck cancers were admitted to our department and 7 died in the hospital, all of whom were middle-aged and elderly patients including 6 males and 1 female. The perioperative mortality rate (POMR) was about 1‰. The causes of death included acute heart failure, rupture of large blood vessels in the neck, hypoxic ischemic encephalopathy due to asphyxia, respiratory failure and cardiopulmonary arrest.ConclusionPreoperative radiotherapy, previous chemotherapy, hypertension, diabetes, advanced clinical stage and postoperative infection are risk factors for perioperative mortality of head and neck cancer.
Highlights
Head and neck cancers are aggressive cancers, most clinical studies focused on the prognosis of patients with head and neck cancer
The perioperative mortality rate (POMR) of Head and neck cancers (HNC) patients was about 1‰ From January 2010 to December 2019, a total of 6576 HNC (4015were male and 2561 were female) patients admitted to our hospital who were ready to accept or had undergone surgery, with an average age of (48.56 ± 3.21) years
We found from January 2010 to December 2019, the POMR of HNC patients in our hospital was about 1‰ which was significantly lower than 0.5% ~ 1.5% mortality rate reported in 2007 [8]
Summary
Head and neck cancers are aggressive cancers, most clinical studies focused on the prognosis of patients with head and neck cancer. Head and neck cancers (HNC) are aggressive cancers that usually have a poor prognosis. Despite the therapeutic advances in the last 30 years, the 5-year survival rate of patients with HNC has not obviously improved [4, 5]. We systematically reviewed the medical records of 6576 HNC patients who received or planned to undergo surgery in our hospital from January 2010 to December 2019. Infection and hypertension were correlated with poor overall survival of HNC patients. Preoperative radiotherapy, previous chemotherapy, hypertension, diabetes, advanced clinical stage and postoperative infection are risk factors for perioperative death of HNC
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