Perioperative Kidney Function of Cardiac Surgery Patients with Impaired Glucose Metabolism

Abstract

Aimto study influence of impaired glucose metabolism on perioperative kidney function of cardiac surgery patients with coronary artery disease (CAD). Material and methodsretrospective analysis of 354 high-risk randomly selected patients with CAD who were discharged after cardiac surgery. For all patients performed laboratory tests, ECG, ECHO, coronary angiography and surgical myocardial revascularization in 194 cases, for 160 patients except CABG we performed correction of postinfarction aneurysm of left ventricle or valves pathology. Resultsimpaired glucose metabolism was found in 251 (70.9%) patients, between which type 2 diabetes mellitus (DM) had 90 (25.4%) pts, impaired glucose tolerance (IGT) – 161 (45.4%). Glomerular filtration rate (GFR) was lower in patients with impaired glucose metabolism (see table 1).Blood parameters and GFR in the perioperative period of patients depending on glucose metabolism, n=354Acute kidney injury (AKI) in postoperative period occurred in 10 (2.8%) patients, between which 6 (60%) had type 2 DM, 2 (20%) – IGT, 2 (20%) – with normal glucose metabolism. None of the patients required renal replacement therapy due to timely correction of drug therapy. Conclusionscardiac surgery patients with coronary artery disease in 70.9% cases had impaired glucose metabolism. Analyses of laboratory parameters in perioperative period had shown decrease of kidney function especially in patients with type 2 DM. AKI occurred in 10 patients, between which 80% had impaired glucose metabolism.