Perioperative fluid managment and postoperative complications after laparoscopic distal pancreatectomy

Abstract

Presenter: Pablo Barros | Hospital Universitario Fundación Favaloro Background: Despite mortality in pancreatic surgery has decreased over the last decade, morbidity still remains high. One of the most important causes for this is the occu pancreatic fistula. Recent studies have demonstrated the importance of fluid management during the post-operative period in major abdominal surgeries. This finding was observed in colonic surgery as well, demonstrating that the overcharge of fluids increases post-operative complications. We aime to evaluate the impact of fluid management on post-operative complications after videolaparoscopic distal pancreatectomy (VDP). Methods: Descriptive, retrospective study of a prospective database of patients who underwent VDP from November 2011 to September 2018. Thirty patients were evaluated and divided into two different groups according to the fluid management protocol used (restrictive or liberal). The data were collected from the anesthesia`s protocols and nursery reports (until 3rd post-operative day). Demographics, length of stay, kind of fluid management and complications were analyzed. For statistical analysis SPSS®v.21 was used (p= < 0.05 was considered significant) Results: Out of 30 patients, 17 (%) were male, mean age was 55 years(r 19-82); 17 patients (57%) were included in liberal group (LG) and 13 (43%) in restrictive group (RG). Twenty-three patients developed complications;16 (53 %) belonged to LG whereas7 (23 %) to RG(p=0,01). Fourteen patients of LG vs. 6 patients of RG had post-operative pancreatic fistula (p=0.04). There were 7 patients (23 %) in LG and 4 (13 %) patients in RG with POPF-CS (13 %, p=ns). 90-day-mortality was 3.3 % Conclusion: After videolaparoscopic distal pancreatectomy, liberal fluid administration at the perioperative period is associated with an increase in the incidence of complication, specially the development of POPF.