Abstract
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder leading to low platelet count and an increased risk of bleeding. Major joint replacement surgery in a patient with ITP can be associated with severe postoperative bleeding. We present our experience of perioperative management in a patient with severe refractory chronic idiopathic thrombocytopenic purpura who successfully underwent a cemented total knee replacement.
Highlights
Refractory chronic immune thrombocytopenic purpura (ITP) is an auto-immune disorder with persistently low platelet count which is unresponsive to any recognised modality of treatment without unacceptable toxicity1)
We present a case report of a 61-year-old male patient with severe chronic refractory Idiopathic thrombocytopenic purpura (ITP) who underwent cemented total knee replacement with careful and meticulous perioperative management
This report describes a case of severe refractory chronic ITP undergoing cemented total knee replacement surgery for severe osteoarthritis of the knee
Summary
Rohit Singhal, MS (Ortho), MRCSEd1, Veera Gudimetla, FRCA2, Andrew Stewart, FRCP Edin, FRCPath[3], Karen L Luscombe, FRCS (Tr & Orth)[1] and Charalambos P Charalambous, MSc, MD, FRCS (Tr & Orth)[4]. Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder leading to low platelet count and an increased risk of bleeding. Major joint replacement surgery in a patient with ITP can be associated with severe postoperative bleeding. We present our experience of perioperative management in a patient with severe refractory chronic idiopathic thrombocytopenic purpura who successfully underwent a cemented total knee replacement
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