Periodontitis and Hereditary Epidermolysis Bullosa: A Rare Case Report and Review

Abstract

Hereditary epidermolysis bullosa (EB) refers to a group of rare genodermatoses and mutational impairment of the structural and functional integrity of skin, i.e., intra-epidermal adhesion and dermo-epidermal anchorage. It is a group of inherited heterogenous mechano- bullous disease that appears on the skin (Fragile) and mucosa (mucous membrane) in the form of blisters associated with minimal mechanical trauma. It is a dermatological condition formed in severe auto-immune disease. EB dystrophica has been presented with various oral manifestations, and earlier dental treatment was restricted to an extraction of all permanent teeth with a construction of complete denture. However, patients suffering from EB also respond well to conventional periodontal therapy. We present the case report of the 20-year-old female patient diagnosed with EB, who reported with the chief complaint of gingival bleeding and difficulty in chewing food due to the mobile teeth. A comprehensive interdisciplinary treatment planning was employed. We find this case report interesting, being one of the rare conditions, reporting periodontal alterations in the patient suffering from EB.