Periodontal Regenerative Therapy Using Enamel Matrix Derivative in Patient with Chronic Periodontitis: a 3-year 6-month Follow-up Report.

Abstract

Here, we report a case of chronic periodontitis requiring periodontal regenerative therapy. The patient was a 73-year-old man who visited Tokyo Dental College Suidobashi Hospital with the chief complaint of gingival swelling and mobile tooth in the mandibular incisor region. An initial examination revealed that 33% of sites had a probing depth (PD) of≥4 mm and 27% bleeding on probing. Radiographic examination revealed bone resorption extending as far as the root apex in #32 and 47, vertical bone resorption in #37, and horizontal resorption in other regions. Based on a clinical diagnosis of moderate chronic periodontitis, initial periodontal therapy was carried out followed by periodontal surgery. The patient's oral health-related quality of life was also assessed at the time of each periodontal assessment. Surgical periodontal therapy was subsequently performed at selected sites. Periodontal regenerative therapy using enamel matrix derivative was performed on #37. Other sites with a PD of ≥4 mm were treated with open flap debridement, and scaling and root planing. Following reevaluation, the patient was placed on supportive periodontal therapy. The patient's periodontal condition has remained stable over a 3-year 6-month period. The patient's oral health-related quality of life showed a marked improvement after periodontal therapy.