Abstract
In a cross-sectional study that included all newborns admitted to the neonatal intensive care of Tishreen University Hospital from October 2019 for one year and who fulfilled clinical and laboratory criteria for early neonatal sepsis, blood samples were drawn for laboratory analysis (CBC, CRP) with a blood culture.
Highlights
Neonatal sepsis contributes significantly to neonatal morbidity and mortality and is an ongoing major global public health challenge in developing countries
The current study found that the most prevalent risk factor for early neonatal infection was a cesarean section, followed by maternal infections, male newborn sex, low birth weight, prematurity, maternal age greater than 30 years and less than 20 years, early rupture of membranes, need for resuscitation, and Meconium amino fluid
The current study confirmed an important prevalence of early neonatal sepsis in Tishreen University Hospital with its association with many risk factors; the most prevalent factors were cesarean section, the gender of the male newborn, low birth weight, and prematurity
Summary
Neonatal sepsis contributes significantly to neonatal morbidity and mortality and is an ongoing major global public health challenge in developing countries. Neonatal septicemia is a clinical laboratory syndrome caused by the passage of pathogens, their toxins, or their antigens into the blood circulation during the first 72 hours of life [1]. And late neonatal septicemia is the most common problem in the newborn stage that caused high morbidity and mortality rate. It is responsible for (30-50)% of neonatal deaths in developing countries, according to WHO estimates [4]. The pathogens that cause early neonatal sepsis are transmitted through the placenta, during childbirth, or after childbirth [5]. It may be bacterial, viral, or fungal. Streptococcus (group B) is the most common pathogen that causes early neonatal sepsis (50%), followed by E. coli (30%), Listeria, Haemophilus influenza, Enterococci, Staphylococci, and Pneumococci [6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
