Perinatal pathology for women with reproductive losses in anamnesis

Abstract

Perinatal aspects of miscarriage, despite progress in the study of pathogenetic mechanisms, continue to be leading in modern obstetrics. The presence of even one case of miscarriage in a woman’s anamnesis negatively affects her further reproductive function, affects the course and outcome of the next pregnancy, and even pre-pregnancy correction of detected disorders does not always allow to achieve the desired result - the birth of a healthy child. The issues of prediction, prevention, and prevention of perinatal complications require a clear understanding of the mechanism of influence of the threat of spontaneous abortion and premature birth on the fetus. Placental dysfunction can have serious consequences during pregnancy, affecting both mother and baby. Therefore, it is very important to study the relationship between potential risk groups, such as women with a history of recurrent pregnancy loss, and placental dysfunction. Perinatal pathology for women with reproductive losses in anamnesis. Based on the germination of a pathogeny of unmaturing of pregnancy and violations of placenta dysfunction, previous abortions in anamnesis can be related to the enhanced able risk of violations of placenta dysfunction. Comparing primiparous women, in which there were abortions in anamnesis, to the control group of women giving birth, can bring the overvalue of risks, as for the primiparous women of violation of placenta dysfunction more widespread, than for women giving birth. It is set that the most closely-coupled interface from preeclampsia was observed for patients with premature births of <37 weeks of gestation, but not in those, who gave in a term. Found out the theenhanceable risk of preeclampsia at the repeated losses of pregnancy, but only at the presence of an anamnesis of auxiliary genesial technologies. Other research it was not succeeded to find out the higher risk of preeclampsia for women with repeated loss of pregnancy, that it is possible to explain the small population and absence of a clear determination of the sequence of abortions. The repeated loss of pregnancy is a studied not enough problem, which causes serious disturbance in pair which try to create a family. Separate patients can have isolated infertility, repeated spontaneous abortions, or repeated losses in the ІІ and ІІІ trimesters. However much epidemiology information testify to strong intercommunication between these unfavorable results. The set reasons for the repeated loss of pregnancy include a hormonal disbalance, anomalies oogenesis highway, genetic or chromosomal anomalies, psychosocial, autoimmune diseases, and, possibly, immunological incompatibility of mother and fetus.