Abstract

Superoxide dismutase (SOD) (EC 1.15.1.1.) catalyses the dismutation of the superoxide radical anion (\( {\text{O}}_2^{\overline \bullet } \)) according to the equation: $$ 2O_2^{\overline \bullet.} + 2{H^ + } \to {H_2}{O_2} + {O_2}$$ There are various isoenzymes of SOD. Dimeric Cu,Zn-SOD and the tetrmeric Mn-SOD and EC-SOD (EC = extracellular) have been found in animals1,2. The activities of Cu,Zn-SOD and Mn-SOD are highest in liver and kidney3, where Cu,Zn-SOD amounts to 96–98 % of total SOD activity3.

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