Abstract
IntroductionPeriductal stromal sarcoma is an extremely rare malignant fibroepithelial tumor of the breast which is characterized by its biphasic histology with benign ductal elements and a sarcomatous stroma made of spindle cells and lacking phyllodes architecture. Its therapeutic management is based on wide surgery with free margins. Adjuvant therapies are not needed. Periductal stromal sarcoma may evolve into a phyllodes tumor with time, as well as a specific soft-tissue sarcoma. To the best of our knowledge, this tumor has never been described in a child.Case presentationA 14-year-old Arabic boy was presented to our hospital one year ago with a nodule of the right breast that was gradually increasing in size without signs of inflammation. The histological examination after lumpectomy revealed a periductal stromal sarcoma with free surgical margins. No adjuvant treatment was given. At 50 months of close follow-up, no recurrence was observed.ConclusionPeriductal stromal sarcoma in a child is a very rare disease which has the same indolent behavior as it does in adults. Therefore, close follow-up is required.
Highlights
Periductal stromal sarcoma is an extremely rare malignant fibroepithelial tumor of the breast which is characterized by its biphasic histology with benign ductal elements and a sarcomatous stroma made of spindle cells and lacking phyllodes architecture
Case presentation: A 14-year-old Arabic boy was presented to our hospital one year ago with a nodule of the right breast that was gradually increasing in size without signs of inflammation
Periductal stromal sarcoma in a child is a very rare disease which has the same indolent behavior as it does in adults
Summary
Periductal stromal sarcoma (PSS) is an extremely rare neoplasm arising in the connective tissue of the breast, especially from the periductal stroma [1]. In this care report, we describe the first such case in a child reported in the literature. Diagnostic problems due to the lack of phyllodes tumors cause diagnostic problems, because PSS is a distinct, low-grade breast sarcoma with no clinical or radiological specificity. Case presentation We report the clinical case of a 14-year-old Arabic boy with no history of disease who was presented to our hospital one year ago with a nodule of the right breast that was gradually increasing in size. In a follow-up period of 50 months, the patient did not show any symptoms or signs of local or distant recurrence
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