Abstract

Background: Pericardial effusion, though uncommon, poses a significant threat to patient well-being, particularly when associated with underlying malignancies such as breast cancer recurrence. Timely recognition and intervention are crucial for improved prognosis and patient outcomes. Case Presentation: We present the case of a 51-year-old woman with a history of treated breast cancer who presented with rapidly worsening dyspnea. Clinical examination and diagnostic tests revealed a large pericardial effusion secondary to breast cancer recurrence, highlighting the diagnostic and therapeutic challenges associated with this condition. Discussion: Breast cancer recurrence involving the pericardium signifies advanced disease and presents significant management complexities. Evaluation typically involves transthoracic echocardiography and pericardiocentesis, with treatment strategies focusing on systemic chemotherapy and symptom management. Conclusion: Pericardial effusion can serve as an early indicator of breast cancer recurrence and requires a multidisciplinary approach for optimal management. Early recognition and intervention are paramount in improving patient outcomes and quality of life.

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