Abstract
Objectives: Hemodynamic changes, such as changes in blood pressure, heart rate, and hypoxia, are observed during surgical procedures and may be related to pre-operative anxiety. As a result, the current study aims to compare the hemodynamic changes, hypoxia, and anxiety in LASER assisted periodontal therapy and surgical periodontal therapy for pocket reduction.
 Methods: This single blinded randomized controlled observational clinical trial included 30 patients with Stage II,III and Grade B,C periodontitis randomly allocated to surgical periodontal therapy (SurPT) and LASER assisted periodontal therapy(LAPT) groups. The systolic blood pressure(SBP), diastolic blood pressure(DBP), Pulserate(PR), oxygen saturation (SpO2) were assessed before injection of local anaesthesia (LA), after LA, during and at the end of procedure. Pre-operative anxiety(POA) was assessed using Amsterdam pre-operative anxiety and information scale(APOAI) before starting the procedure. Statistical analysis was done using student t-test for intergroup and repeated measures of ANOVA for intragroup analysis.
 Results: SBP and HR were significantly greater in SurPT group at all time intervals compared to LAPT group (P
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