Abstract
Reliable, sensitive, and accurate tests are needed to assess animal models of brain injury. The Garcia score is a neuro behavioral measure that has been used in many murine studies. However, despite its widespread use, there are no detailed video descriptions of the steps to properly perform and grade the Garcia test on rats. Consequently, there has been significant variation in its performance and reliability, calling for greater standardization. The Garcia score is comprised of six measures: spontaneous activity, symmetry in the four limbs, fore paw outstretching, climbing, body sensation, and response to vibrissae touch. Each component is scored with a minimum of zero or one and a maximum of three, with the highest total score of 18. This report systematically and clearly describes how each component of the Garcia score is performed and graded with an accompanying video illustration. The purpose of this report is to assist researchers in implementing the Garcia test and to help standardize the use of this measure across studies.
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