Abstract
Background The diagnosis of acute myocarditis is described to be challenging. Novel techniques like native and contrast enhanced T1 mapping have proven to be superior to standard sequences for differentiation between healthy individuals and acute myocarditis, but a comparison in the clinical setting is not yet done. We sought to assess the diagnostic performance of native and contrast enhanced T1 mapping compared to T2w-imaging, Relative Enhancement (RE) in T1w as well as Late-Gadolinium-Enhancement (LGE).
Highlights
The diagnosis of acute myocarditis is described to be challenging
T2-signal intensity (SI) of potential lesions was compared to remote myocardium and the standard deviation
AUC for T2w imaging (T2-SI compared to remote) was 66 % (p = 0.014) with an optimal cutoff of 1.5 standard deviations above remote (Specificity: 64%; Sensitivity: 68%)
Summary
Performance of native and contrast enhanced T1 mapping to detect myocardial damage in patients with suspected myocarditis: A head to head comparison of different CMR-techniques. Jonathan Nadjiri*, Eva Hendrich, Albrecht Will, Cornelia Pankalla, Nerejda Shehu, Stefan Martinoff, Martin Hadamitzky
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