Abstract
Evaluation of: Yankaskas BC, Haneuse S, Kapp JM, Kerlikowske K, Geller B, Buist DSM; For the Breast Cancer Surveillance Consortium: Performance of first mammography examination in women younger than 40 years. J. Natl Cancer Inst. 102(10), 692–700 (2010). By using pooled data from six mammography registries across the USA, 117,737 women aged 18–39 years were identified who had received their first mammography in the period 1995–2005. A distinction was made between diagnostic mammography for women who presented with a breast problem (n = 30,956), and screening mammography (n = 86,781). The age-adjusted positive predictive value of screening mammography was 1.3% (95% CI: 1.1–1.5%), as compared with 14.6% (95% CI: 13.3–15.8%) for diagnostic mammography. Considering the high recall rates, the high number of false-positive test results and the low cancer detection rate, the appropriateness of mammography for women younger than 40 without symptoms is questionable.
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