Abstract
Although titanium remains as the prevalent material in dental implant manufacturing new zirconia-based materials that overcome the major drawbacks of the standard 3Y-yttria partially-stabilized zirconia (Y-TZP) are now emerging. In this study, a new ceramic nanocomposite made of alumina and ceria-stabilized TZP (ZCe-A) has been used to produce dental implants with the mechanic and topographic characteristics of a pilot implant design to evaluate bone and soft tissue integration in a dog model (n = 5). Histological cross-section analysis of the implanted ceramic fixations (n = 15) showed not only perfect biocompatibility, but also a high rate of osseous integration (defined as the percentage of bone to implant contact) and soft tissue attachment. This clinical success, in combination with the superior mechanical properties achieved by this Al2O3/Ce-TZP nanocomposite, may place this material as an improved alternative of traditional 3Y-TZP dental implants.
Highlights
Dental implants are considered an essential treatment modality for the replacement of missing teeth.There is a great number of data proving the significant and predictable performance of implants in partially- and totally-edentulous arches in the long-term
This is why the development of new mechanically-improved ceramic materials for dental implant applications have to be coupled with a deep material/tissue interaction study
We study the suitability of an Al2 O3 /ceria-stabilized tetragonal zirconia polycrystals (Ce-TZP) ceramic nanocomposite for dental implant applications in terms of osseous integration, defined as the percentage of bone to implant contact and soft tissue attachment
Summary
Dental implants are considered an essential treatment modality for the replacement of missing teeth.There is a great number of data proving the significant and predictable performance of implants in partially- and totally-edentulous arches in the long-term. Dental implants are considered an essential treatment modality for the replacement of missing teeth. The aesthetic outcome of implants placed in the anterior zone is challenging [1,2]. It is well known that, depending on the particular functionality of the different material surfaces present in a dental implant, the chemical, mechanical, topographic, and electrical material properties will undoubtedly contribute to the performance of a biomaterial/prosthetic device. This is why the development of new mechanically-improved ceramic materials for dental implant applications have to be coupled with a deep material/tissue interaction study
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