Abstract
BackgroundThis paper describes the National Electrical Manufacturers Association (NEMA) system performance of the Discovery MI 3-ring PET/CT (GE Healthcare) installed in Bruges, Belgium. This time-of-flight (TOF) PET camera is based on silicon photomultipliers instead of photomultiplier tubes.MethodsThe NEMA NU2-2012 standard was used to evaluate spatial resolution, sensitivity, image quality (IQ) and count rate curves of the system. Timing and energy resolution were determined.ResultsFull width at half maximum (FWHM) of spatial resolution in radial, tangential and axial direction was 4.69, 4.08 and 4.68 mm at 1 cm; 5.58, 4.64 and 5.83 mm at 10 cm; and 7.53, 5.08 and 5.47 mm at 20 cm from the centre of the field of view (FOV) for the filtered backprojection reconstruction. For non-TOF ordered subset expectation maximization (OSEM) reconstruction without point spread function (PSF) correction, FWHM was 3.87, 3.69 and 4.15 mm at 1 cm; 4.80, 3.81 and 4.87 mm at 10 cm; and 7.38, 4.16 and 3.98 mm at 20 cm. Sensitivity was 7.258 cps/kBq at the centre of the FOV and 7.117 cps/kBq at 10-cm radial offset. Contrast recovery (CR) using the IQ phantom for the TOF OSEM reconstruction without PSF correction was 47.4, 59.3, 67.0 and 77.0% for the 10-, 13-, 17- and 22-mm radioactive spheres and 82.5 and 85.1% for the 28- and 37-mm non-radioactive spheres. Background variability (BV) was 16.4, 12.1, 9.1, 6.6, 5.1 and 3.8% for the 10-, 13-, 17-, 22-, 28- and 37-mm spheres. Lung error was 8.5%. Peak noise equivalent count rate (NECR) was 102.3 kcps at 23.0 kBq/ml with a scatter fraction of 41.2%. Maximum accuracy error was 3.88%. Coincidence timing resolution was 375.6 ps FWHM. Energy resolution was 9.3% FWHM. Q.Clear reconstruction significantly improved CR and reduced BV compared with OSEM.ConclusionSystem sensitivity and NECR are lower and IQ phantom’s BV is higher compared with larger axial FOV (AFOV) scanners like the 4-ring discovery MI, as expected from the smaller solid angle of the 3-ring system. The other NEMA performance parameters are all comparable with those of the larger AFOV scanners.
Highlights
Over the last years, positron-emission tomography (PET) has benefited enormously from various developments, including time-of-flight (TOF), point spread function (PSF) correction and the introduction of solid-state photomultipliers instead of vacuum photomultiplier tubes [1, 2]
System sensitivity and noise equivalent count rate (NECR) are lower and image quality (IQ) phantom’s Background variability (BV) is higher compared with larger axial field of view (FOV) (AFOV) scanners like the 4-ring discovery MI, as expected from the smaller solid angle of the 3-ring system
We evaluated the system performance of the Discovery Meaningful Insights PET/Computed tomography (CT) with a 3-ring PET (Discovery MI 3, General Electric (GE) Healthcare, Milwaukee, WI, USA) and compared it with literature data on the similar system with 4 rings (Discovery MI 4), which had been put onto the market before [3]
Summary
Positron-emission tomography (PET) has benefited enormously from various developments, including time-of-flight (TOF), point spread function (PSF) correction and the introduction of solid-state photomultipliers instead of vacuum photomultiplier tubes [1, 2]. Each block is coupled with 6 (in the axial direction) × 3 (in the in-plane direction) silicon photomultiplier arrays (SiPM). The National Electrical Manufacturers Association (NEMA) NU2-2012 standards [4] were used for the evaluation, as in most of the recent literature [3, 5,6,7,8,9,10,11,12,13,14,15,16,17]. This paper describes the National Electrical Manufacturers Association (NEMA) system performance of the Discovery MI 3-ring PET/CT (GE Healthcare) installed in Bruges, Belgium. This time-of-flight (TOF) PET camera is based on silicon photomultipliers instead of photomultiplier tubes
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