Abstract
A recent report in this journal by Rawlins and Roberts (1) compared 6 commercial third-generation assays for thyroid-stimulating hormone (TSH). The authors reported a functional sensitivity of 0.039 mIU/L for the ADVIA Centaur® TSH-3, in contrast to the manufacturer’s claim of 0.019 mIU/L (2). Rawlins and Roberts (1) cited a single earlier ADVIA Centaur study (3), which they claim agrees with their results; however, the cited study actually evaluated the ADVIA Centaur TSH, a second-generation TSH assay that is different from the TSH-3. Previous publications …
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