Performance, biochemical and haematological responses, and relative organ weights of laying hens fed diets supplemented with prebiotic, probiotic and synbiotic

Shirley Gee Hoon Tang,Yin Wan Ho,Chin Chin Sieo,Wan Zuhainis Saad,Kalavathy Ramasamy,Hee Kum Wong

doi:10.1186/s12917-017-1160-y

Abstract

BackgroundThe increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs. Prebiotic, probiotic and their combination as a synbiotic have been considered as potential alternatives. This study aimed to investigate the effects of a prebiotic (isomaltooligosaccharide, IMO), a probiotic (PrimaLac®), and their combination (synbiotic) on hen performance, biochemical and haematological responses, and relative organ weights from 20 to 52 weeks of age.ResultsSupplementation of 1% IMO (PRE), 0.1% PrimaLac® (PRO) and 1% IMO + 0.1% PrimaLac® (SYN) improved (P < 0.05) feed intake and egg production at 20–36 weeks of age; body weight gain, feed conversion ratio and egg mass at 20–36 and 20–52 weeks of age; and egg weight at 20–36, 37–52 and 20–52 weeks of age. Compared to control-fed hens at 20–36 weeks of age, PRO- and SYN-fed hens produced less (P < 0.05) small size eggs while SYN-fed hens produced more large size eggs. From 37 to 52 weeks of age, PRE-, PRO- or SYN-fed hens produced less (P < 0.05) medium size eggs, and more large and extra-large size eggs. PRE, PRO or SYN supplementation decreased (P < 0.05) the serum total cholesterol at 36 weeks of age, and serum low-density lipoprotein (LDL) cholesterol, alanine aminotransferase (ALT) and alkaline phosphatase (ALP) at 36 and 52 weeks of age. At 36 and 52 weeks of age, supplementation of PRE, PRO or SYN increased (P < 0.05) lymphocyte percentage and decreased (P < 0.05) heterophil percentage, leading to a lower heterophil to lymphocyte (H/L) ratio. No significant differences were observed in the relative weights of the heart, liver, ovary, pancreas and spleen of all dietary treatment groups.ConclusionsSupplementation of PRE, PRO or SYN improved performance, serum total cholesterol, LDL cholesterol, ALT, ALP and H/L ratio of hens from 20 to 52 weeks of age. These results demonstrated the use of PRE, PRO and SYN as alternative feed additives to AGPs for improving the health and productivity of hens, while PRO is the best for commercial layer production to yield maximum profit.

Highlights

The increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs
There are several studies in which the supplementation of prebiotics, probiotics or synbiotics in poultry feeds has improved the feed intake of broiler chickens and laying hens [31,32,33], and it has been suggested that the improved feed intake is most likely due to the ability of the probiotic and prebiotic to stimulate the appetite of laying hens [12, 32]
There are some studies which reported that the addition of prebiotics, probiotics or synbiotics had no effect on the feed intake of laying hens or broiler chickens [8, 21, 23]

Summary

Introduction

The increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs. Probiotics and prebiotics can be considered as natural feed additives which may be able to provide an effect similar to that of AGPs. The supplementation of probiotics in poultry feeds has been reported to improve growth performance [1,2,3,4,5,6,7,8,9,10], nutrient retention [11, 12], caecal microbial balance [2, 8, 11] and immune response [4, 13], and lower cholesterol levels of chickens [3, 5,6,7, 10, 13]. A synbiotic product has the potential synergistic effect of promoting the proliferation of existing strains of beneficial bacteria in the colon as well as improving the survival and growth of newly added probiotic strains [17]

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