Performance and Applications of Semifluidized Bioreactors – A Review

Abstract

AbstractThis paper reviews the design features and performance characteristics of semifluidized bed bioreactors. Both biofilm reactors and immobilized enzyme bioreactors have been analysed. Also, both two phase (liquid – solid) and three phase (gas – liquid – solid) operations are considered. Apart from the hydrodynamic parameters (semifluidization velocity, bed expansion ratio, height of packed section formed, fractional fluid holdups in both fluidized and packed sections), all other operating/system parameters affecting reactor performance such as axial dispersion, intrinsic kinetics of bioconversion (mostly nonlinear), the effectiveness factor and Thiele – type modulus have also been surveyed. The specific advantages and attractive features of these bioreactors have been highlighted based on data from successful case studies such as bioplastic synthesis, biodiesel manufacture, Xanthan gum production and aerobic waste water treatment with and without LPO (Liquid Phase Oxygen) utilization.