Abstract
The concept of transepidermal elimination (TE) was introduced by Mehregan 1 in 1968. In this process, the epidermis shows changes of pseudoepitheliomatous hyperplasia and channels through which material from the dermis extrudes. The extruded matter frequently consists of material foreign to the dermis (as seen in calcinosis cutis or osteoma perforans), altered collagen (as seen in reactive perforating collagenosis, necrobiosis lipoidica, or granuloma annulare), or altered elastin (as occurring in pseudoxanthoma elasticum or elastosis perforans serpiginosa). 2 The mechanism of TE is unknown. We describe a patient who had perforating rheumatoid nodules (RNs) that histologically exhibited the features of TE. While we believe this phenomenon is not rare, we could find no similar cases reported in the literature. Report of a Case A 54-year-old woman was first seen in March 1981 for infection of a nodule on the anterior part of the shin. She had had a history of rheumatoid
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
